Medetomidine
- What is it? A strong sedative, like xylazine but much stronger. Not an opioid.
- Effects: Last a long time (90 minutes or several hours). Deep sleepiness (on the nod, heavily sedated).
- Passing out. People may be hard to wake up.
- Slow breathing, heart rate, and blood pressure.
- May cause hallucinations or confusion.
- Dizziness, nausea, vomiting.
- Medetomidine Withdrawal: Can start quickly and be very serious. Signs to go to the hospital:
- can’t stop throwing up.
- chest pain.
- going in and out of awareness
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What is it? Unregulated fentanyl-like drug (opioid).
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Test your drugs with fentanyl test strips. A positive result could mean para-fluorofentanyl or other types of fentanyl are in your drugs.
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Effects:
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Deep sleepiness (on the nod, heavily sedated).
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Passing out. People may be hard to wake up.
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Slow breathing, heart rate, and blood pressure
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What is it? A very strong unregulated opioid.
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Test your drugs with Nitazene test strips. A positive result could mean Nitazenes are in your drugs.
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Effects:
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Deep sleepiness (on the nod, heavily sedated).
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Passing out. People may be hard to wake up.
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Slow breathing, heart rate, and blood pressure.
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Very low or no pulse.
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What is it? A strong opioid.
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Test your drugs with fentanyl test strips. A positive result could mean fentanyl is in your drugs.
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Fentanyl was found to be stronger than expected. People who use unregulated (street) fentanyl may be at greater risk for overdose/ drug poisoning.
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Effects:
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Slows breathing and heart rate.
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People may be hard to wake up (heavily sedated).
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Memory loss.
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Feeling of a stiff or tight chest.
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What is it? A strong sedative. Not an opioid.
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Flubromazepam is a strong long-acting benzodiazepine. Effects are strong and last a long time
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Gidazepam is a long-acting benzodiazepine. Effects may not be as strong as other benzodiazepines but last a lot longer.
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Effects:
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Deep sleepiness (on the nod, heavily sedated).
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Passing out. People may be hard to wake up.
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Slow breathing, heart rate, and blood pressure.
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Blackouts (memory loss).
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Slurred speech, trouble focusing eyes, poor balance.
What to do:
- Stay with anyone on the nod and watch for signs of an overdose.
- Follow the 5 steps to respond to an opioid overdose:
- Shout their name and shake their shoulders.
- Call 911 if they won’t wake up or if breathing is very slow or not at all.
- Give naloxone.
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Fentanyl, para-fluorofentanyl, and nitazenes and are opioids. Naloxone will work on these drugs.
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Medetomidine and benzodiazepines are not opioids. Naloxone cannot stop the effects of medetomidine or benzodiazepines. Give naloxone because it will work on opioids that may be mixed in the drugs.
- Check that the person is breathing regularly. They may not wake up right away. Perform rescue breathing or give oxygen if you can.
- Additional doses of naloxone may be needed. Give another dose every 2-3 minutes until breathing is back to normal.
- If they are very sedated (sleepy) but still breathing, encourage them to keep breathing.
- Stay with them until help arrives.